Do large CEXes actively block/close accounts of people depositing mixed BTC?

Lets say my friend has some BTC that he/she run through coinjoin/whirlpool (he/she may be using Sparrow, Samourai or Wasabi wallets) and he/she would like to sell that on a CEX. Would any major exchange (like Binance, Coinbase, Kraken, etc.) block and close his/her account for trying to do such outrageous thing as staying private or maybe they don't care that much? Or maybe they will be ok with that as long as my friend's deposit is relatively "small"? Or maybe he/she just needs some dumb obfuscation of mixing like doing a few (~10) normal "hops" (sth like Samourai's "Ricochet" transaction) between clean accounts and he/she will be good? (;

As you clearly see, I'm asking for a friend.